Anilhttps://www.nature.com/articles/s43587-021-00060-4
We commonly think of air pollution as a cause of lung diseases such as asthma, chronic obstructive lung disease (COPD) and emphysema. However even short-term exposure to polluted air may accelerate brain aging and increase the risk of dementia according to an article published in Nature and reported in the New York Times. (use links above)
In this Nature Aging observational study, they studied 954 men with an average age of 69 living the greater Boston area. Over 28 days they were given a MMSE or Mini-Mental State Examination to study their cognitive ability. The highest score in the MMSE is 30, with a score of less than 25 suggesting mild dementia.
During the study, PM2.5 air quality was measured and averaged 10.77. PM2.5 are fine particulate pollutants such as soot with a diameter of 2.5microns or less, which are small enough to enter the lungs, the bloodstream and cerebral circulation. During the weeks with the highest PM2.5 pollution levels, the men were 63% more likely to score below 25 on the MMSE.
Another “intriguing” aspect of this study was that men taking NSAIDs such as aspirin, ibuprofen, and naproxen were partially protected from the negative cognitive effects of pollution. The authors speculated that the NSAIDs may provide anti-inflammatory protection from pollutants.
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